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Title:

Reply to “The 1977 H1N1 Influenza Virus Reemergence Demonstrated Gain-of-Function Hazards”

Authors:

Michelle Rozo, Gigi Kwik Gronvall

Date posted:

September 29, 2015

Publication type:

Letter

Publication:

mBio 2015;6(5):e01524-15

Publisher:

American Society for Microbiology

DOI:

10.1128/mBio.01524-15

See also:

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Introduction:

We thank Martin Furmanski for his interest in our article (1) concerning the unnatural origins of the 1977 H1N1 influenza virus strain. In his Letter to the Editor, he challenges our assertion that to date, there has been no real-world example of a laboratory accident that has led to a global epidemic, and he states that we ourselves concluded that the virus “originated in a microbiology laboratory and its release was unintentional,” to which he added that “which laboratory is responsible matters little in the GoF debate” (2). This is a mischaracterization of our findings.