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Global Health Technical Brief February 2008
Since December 2003, highly pathogenic avian influenza (HPAI) H5N1 has infected and killed millions of poultry and wild birds across Asia, Europe, the Near East and parts of Africa. Also known as ‘bird flu’ and avian influenza (AI), HPAI H5N1 is endemic to several regions of the world and has demonstrated transmissibility to humans. While the spread of H5N1 virus from person-to-person is currently rare and unsustained, H5N1 continues to pose a significant threat to public health and economies worldwide.